Family name Santiago De Jesus (Santiago De Jesus 
) , worldwide, is a very rare cognomen. The surname Santiago De Jesus is habitual in Chile, where it is a very rare surname, Spain, where it is an extremely rare surname, and Mexico. Measured by absolute frequency, it is commonest in Chile, the United States, and Mexico. More frequently, Santiago De Jesus is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Santiago De Jesus | Spain, Dominican Republic, Chile, Ecuador, Costa Rica |
Cruz, Molina, Campos, Montero, Camacho, Cabahug, Martinez, Gutierrez, Hernandez, Rivas Lopez, Maestro Saavedra, Rodas Gonzalez, Lindao Hermenejildo, and Martinez Ramirez